Which class of gene products is associated with HLA-A, HLA-B, and HLA-C?

Which class of gene products is associated with HLA-A, HLA-B, and HLA-C?

• A. Class II
• B. Class III
• C. Class I
• D. Class IV

Answer: (C)

The class of gene products associated with HLA-A, HLA-B, and HLA-C is Class I. These are all major histocompatibility complex (MHC) class I molecules, which play a crucial role in the immune system, particularly in presenting endogenous antigens (derived from within the cell) to CD8+ cytotoxic T cells. MHC class I molecules are expressed on nearly all nucleated cells and are essential for the recognition and elimination of infected or malignant cells. They present peptide fragments that originate from the proteins synthesized within the cell, which helps the immune system distinguish healthy cells from those that are compromised. In contrast, Class II molecules (which include HLA-DP, HLA-DQ, and HLA-DR) are primarily expressed on professional antigen-presenting cells, like B cells and macrophages, and are involved in presenting exogenous antigens to CD4+ helper T cells. Class III molecules consist of various other proteins involved in immune responses, such as complement proteins, but are not directly linked to the antigen presentation role of the other classes. Class IV is not a recognized category in the MHC classification system. Hence, the association of HLA-A, HLA-B, and H

The class of gene products associated with HLA-A, HLA-B, and HLA-C is Class I. These are all major histocompatibility complex (MHC) class I molecules, which play a crucial role in the immune system, particularly in presenting endogenous antigens (derived from within the cell) to CD8+ cytotoxic T cells.

MHC class I molecules are expressed on nearly all nucleated cells and are essential for the recognition and elimination of infected or malignant cells. They present peptide fragments that originate from the proteins synthesized within the cell, which helps the immune system distinguish healthy cells from those that are compromised.

In contrast, Class II molecules (which include HLA-DP, HLA-DQ, and HLA-DR) are primarily expressed on professional antigen-presenting cells, like B cells and macrophages, and are involved in presenting exogenous antigens to CD4+ helper T cells. Class III molecules consist of various other proteins involved in immune responses, such as complement proteins, but are not directly linked to the antigen presentation role of the other classes. Class IV is not a recognized category in the MHC classification system. Hence, the association of HLA-A, HLA-B, and H